The role of myosin Va in secretory granule trafficking and exocytosis.
نویسندگان
چکیده
It emerges that myosin Va plays multiple roles in the trafficking of SGs (secretory granules). In addition to a function in the capture and transport of newly formed SGs in the F-actin-rich cortex, myosin Va is implicated in late transport events of these organelles, which precede their exocytosis. Consistent with these roles, interactions of myosin Va with an array of well-known proteins involved in regulated protein secretion have been documented.
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عنوان ژورنال:
- Biochemical Society transactions
دوره 34 Pt 5 شماره
صفحات -
تاریخ انتشار 2006